Endocrine stress responsivity and social memory in 3xTg-AD female and male mice: A tale of two experiments

ET Nguyen, D Selmanovic, M Maltry, R Morano… - … and Behavior, 2020 - Elsevier
… heightened stress-induced corticosterone levels and … Although 3xTg-AD mice do not
display elevated basal … 3xTg mice (ie, 4 months) already exhibit altered mRNA expression of …

[HTML][HTML] Impact of chronic risperidone use on behavior and survival of 3xTg-AD mice model of Alzheimer's disease and mice with normal aging

V Torres-Lista, S López-Pousa… - Frontiers in …, 2019 - frontiersin.org
… the 3xTg-AD (s) mice, an increase in the number of “changed3xTg-AD mice and their worse
capacity to cope with stress; … decreased the number of plaques of in the cortex and in the …

IL-6 trans-signaling in the brain influences the behavioral and physio-pathological phenotype of the Tg2576 and 3xTgAD mouse models of Alzheimer's disease

A Escrig, C Canal, P Sanchis… - Brain, Behavior, and …, 2019 - Elsevier
… traits changed similarly in AD mice, with the exception of … male and female mice showed
increased exploratory behavior in the … , 40 and 42 levels were much lower in the 3xTg-AD

[HTML][HTML] Investigation of anxiety-and depressive-like symptoms in 4-and 8-month-old male triple transgenic mouse models of Alzheimer's disease

D Várkonyi, B Török, E Sipos, CL Fazekas… - International Journal of …, 2022 - mdpi.com
… in the 3xTg-AD mice immobility latency was increased at 8-… results, 4-month-old 3xTg-AD
mice reacted to stress with an … that some behavioral characteristics of 3xTg-AD mice might be …

Age-related changes in social behaviours in the 5xFAD mouse model of Alzheimer's disease

F Kosel, PT Munoz, JR Yang, AA Wong… - Behavioural Brain …, 2019 - Elsevier
… Evidence for increased sociability in the 3xTg-AD mouse … accelerated pathology, transgenic
5xFAD mice exhibit deficits … exhibit abnormal responses to social odour cues and altered

[HTML][HTML] … -induced responses, anxiety, hypercortisolemia, and organometry of early peripheral immunoendocrine impairment in adult 3xTg-AD mice and their long …

R Baeta-Corral, M De la Fuente… - Behavioural Brain …, 2023 - Elsevier
… and female 3xTg-AD mice exhibit worse nesting behavior than … normal levels, an activated
central HPA axis with altered … receptor, and ACTH in several stress- and emotionality-related …

[HTML][HTML] Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer's disease-associated markers in 3xTg-AD mice

M Kapadia, MF Mian, D Ma, CP Hutton, A Azam… - Alzheimer's Research & …, 2021 - Springer
… early manifestations of systemic autoimmunity, increased … to 3xTg-AD males, 1-year-old
3xTg-AD females still show … in the context of the altered 3xTg-AD phenotype, the current study …

[HTML][HTML] … in the basolateral amygdala and cholinergic fiber loss in the cortex but not cognitive behavioral symptoms in a triple transgenic mouse model of alzheimer's …

S Farkas, A Szabó, B Török, C Sólyomvári… - Frontiers in …, 2022 - frontiersin.org
… 4-month-old 3xTg-AD mice only after hormone depletion. Three-… (IV) At the structural level,
we were concentrating on … Cognitive z-score was calculated from alteration in the Y-maze; …

Chronic fragmentation of the daily sleep-wake rhythm increases amyloid-beta levels and neuroinflammation in the 3xTg-AD mouse model of Alzheimer's disease

MJ Duncan, LE Guerriero, K Kohler, LE Beechem… - Neuroscience, 2022 - Elsevier
… revealed that sleep fragmentation altered the daily sleep-wake … Our findings of increased
following sleep fragmentation … Sex-dependent alterations in social behaviour and cortical …

Age and gender differences for the behavioral phenotypes of 3xTg Alzheimer's disease mice

T Pairojana, S Phasuk, P Suresh, SP Huang… - Brain Research, 2021 - Elsevier
… Male 3xTg-AD mice exhibit normal sensory and locomotor … behavioral phenotypes for the
two genders of 3xTg-AD mice at … In 3xTg-AD mice, plaques occur at around three months old…